Preheat the oven to 400 F. Line a baking sheet with parchment paper.
Wash and dry the sweetpotatoes well. Using a fork, pierce holes throughout the sweetpotatoes, making sure to go all around the sweetpotato.
Place on the baking sheet and bake in the preheated oven for about 45 minutes, until a fork can pierce them easily. I recommend turning the sweetpotatoes over once about halfway through cooking.
While the sweetpotatoes are roasting, prepare the ground beef. In a large skillet, add the olive oil, diced onion, ground beef, garlic powder, onion powder, paprika, salt, and pepper.
Break the beef apart into small pieces and cook until medium high heat. Make sure to stir infrequently so that the beef can brown. Once cooked through and no longer pink, remove the skillet from the heat and set aside.
Prepare the sauce. Add the mayonnaise, pickle juice, sugar, garlic powder, onion powder, paprika, turmeric, and salt to taste to a small bowl or jar. Whisk well to combine (or if using a jar, cover and shake the jar). Set aside.
Once the sweetpotatoes are done roasting, let them cool for about 5 minutes. Slice them in half lengthwise.
Assemble the stuffed sweetpotatoes. Top each sweetpotato evenly with the ground beef, cheddar cheese, shredded lettuce, diced tomatoes, and chopped pickles.
Sprinkle sesame seeds on top and drizzle on the burger sauce.